https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Omega-3 polyunsaturated fatty acids status and cognitive function in young women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38158 2) or obese weight (OB: BMI ≥30.0 kg/m2). Participants completed a computer-based cognition testing battery (IntegNeuro™) evaluating the domains of impulsivity, attention, information processing, memory and executive function. The Omega-3 Index (O3I) was used to determine n-3 PUFA status (percentage of EPA (20:5n-3) plus DHA (22:6n3) in the red cell membrane) and the participants were divided into O3I tertile groups: T1 < 5.47%, T2 = 5.47–6.75%, T3 > 6.75%. Potential confounding factors of BMI, inflammatory status (C-reactive Protein), physical activity (total MET-min/wk), alpha1-acid glycoprotein, serum ferritin and hemoglobin, were assessed. Data reported as z-scores (mean ± SD), analyses via ANOVA and ANCOVA. Results: Two hundred ninety-nine women (26.9 ± 5.4 y) completed the study (O3I data, n = 288). The ANOVA showed no overall group differences but a significant group × cognition domain interaction (p < 0.01). Post hoc tests showed that participants in the low O3I tertile group scored significantly lower on attention than the middle group (p = 0.01; ES = 0.45 [0.15–0.74]), while the difference with the high group was borderline significant (p = 0.052; ES = 0.38 [0.09–0.68]). After confounder adjustments, the low group had lower attention scores than both the middle (p = 0.01) and high (p = 0.048) groups. These findings were supported by univariate analyses which found significant group differences for the attention domain only (p = 0.004). Conclusions: Cognitive function in the attention domain was lower in women with lower O3I, but still within normal range. This reduced but normal level of cognition potentially provides a lower baseline from which cognition would decline with age. Further investigation of individuals with low n-3 PUFA status is warranted.]]> Wed 04 Aug 2021 18:23:51 AEST ]]> Association between omega-3 index and blood lipids in older Australians https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24083 Thu 04 Nov 2021 10:38:19 AEDT ]]> Short-term docosapentaenoic acid (22:5 n-3) supplementation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9673 Sat 24 Mar 2018 08:39:16 AEDT ]]> Efficacy of the omega-3 index in predicting non-alcoholic fatty liver disease in overweight and obese adults: a pilot study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26621 Sat 24 Mar 2018 07:34:00 AEDT ]]> Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24117 Sat 24 Mar 2018 07:11:43 AEDT ]]> Association between obesity and omega-3 status in healthy young women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38154 Mon 29 Jan 2024 17:46:57 AEDT ]]>